I assume you're asking if it's OK to run this oil in the transmission of a KX125. This would be transmission oil, not crankcase oil. The crankcase on a two stroke is lubricated by the oil suspended in the fuel the engine ingests. That being said, I would NOT recommend this oil. Why? Because it's designed for four stroke engines without wet clutches. Their website doesn't use the term "friction modifiers" to describe this oil, but I wouldn't be surprised if it contained some. Since the KX has a wet clutch, stick with an oil specifically designed for wet clutch motorcycle transmissions. I could recommend an oil for you, but that always starts the biggest pissing match, so do some research and decide for yourself.